http://www.lung-cancer-blog.com/blogs/lung-cancer-blog.html Lung cancer blog From Lung cancer blog en-us http://www.lung-cancer-blog.com/images/blogs/lung-cancer-blog-78210.jpg http://www.lung-cancer-blog.com/blogs/lung-cancer-blog.html 100111 http://www.lung-cancer-blog.com/blogs/permalinks/7-2011/tgen-presents-lung-cancer-studies.html he Translational Genomics Research Institute (TGen) is presenting two key studies, including one today, at the 14th World Conference on Lung Cancer, July 3-7 in Amsterdam. One study, presented July 4, involved a gene called GLI1, which may limit the effectiveness of the most common combination chemotherapy given to patients with small cell lung cancer (SCLC)........ http://www.lung-cancer-blog.com/blogs/permalinks/4-2011/new-lung-cancer-staging-system.html The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, as per a research studyreported in the recent issue of the Journal of Thoracic Oncology Being able to better define which patients might experience a cancer recurrence is important, particularly given the controversies surrounding the use of adjuvant therapies, especially postoperative radiation treatment (RT), for patients with non-small cell lung cancer (NSCLC)........ http://www.lung-cancer-blog.com/blogs/permalinks/2-2011/new-classification-of-lung-adenocarcinoma.html hree of the world's top lung associations have published a new international multidisciplinary classification of lung adenocarcinoma, the first revision to the classification in six years. The new classification is reported in the February edition of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer (IASLC)........ http://www.lung-cancer-blog.com/blogs/permalinks/2-2011/circulating-dna-amd-progression-of-lung-cancer.html High levels of circulating DNA may indicate faster progression of lung cancer and lower overall survival, as per a research studyreported in the February edition of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer (IASLC)........ http://www.lung-cancer-blog.com/blogs/permalinks/1-2011/lung-cancer-risk-among-tuberculosis-patients.html venthough a clear association of tuberculosis with lung cancer remains to be established, a newly released study reported in the recent issue of the Journal of Thoracic Oncology provides compelling evidence of increased lung cancer risk among people with tuberculosis. Scientists at China Medical University and Hospital in Taiwan randomly selected 1 million patients covered under the country's National Health Insurance (NHI) program. All patients aged 20 years and older with a new diagnosis of tuberculosis between 1998 and 2000 were identified as the exposed cohort and all people without tuberculosis history were the non-exposed cohort. Patients with any cancer diagnosis were excluded to ensure that all participants were cancer-free at the start of both cohorts. Overall, 716,872 adults were eligible for the analysis - 4,480 in the tuberculosis cohort and 712,392 in the non-tuberculosis cohort........ http://www.lung-cancer-blog.com/blogs/permalinks/11-2010/helical-ct-scans-reduce-lung-cancer-mortality.html In a major new study announced recently by the National Cancer Institute, researchers including Brown University biostatistian Constantine Gatsonis and his colleagues found that screening for lung cancer using helical CT scanning reduced lung cancer deaths by 20 percent compared to using chest X-rays........ http://www.lung-cancer-blog.com/blogs/permalinks/10-2010/early-lung-cancer-detection.html Scientists from Northwestern University and NorthShore University HealthSystem (NorthShore) have developed a method to detect early signs of lung cancer by examining cheek cells in humans using pioneering biophotonics technology. "By examining the lining of the cheek with this optical technology, we have the potential to prescreen patients at high risk for lung cancer, such as those who smoke, and identify the individuals who would likely benefit from more invasive and expensive tests versus those who don't need additional tests," said Hemant K. Roy, M.D., director of gastroenterology research at NorthShore........ http://www.lung-cancer-blog.com/blogs/permalinks/10-2010/erlotinib-for-advanced-lung-cancer.html Featured in the October edition of the Journal of Thoracic Oncology (JTO), data from The Tarceva Lung Cancer Survival Treatment (TRUST) confirms the safety and efficacy profile of erlotinib, a highly potent oral active, reversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine-kinase (TK) activity in a large heterogeneous non-small cell lung cancer (NSCLC) population........ http://www.lung-cancer-blog.com/blogs/permalinks/1-2010/childhood-harms-can-lead-to-lung-cancer.html Adverse events in childhood have been associated with an increase in the likelihood of developing lung cancer in later life. Scientists writing in the open access journal BMC Public Health describe how the link is partly explained by raised rates of cigarette smoking in victims of childhood trauma, but note that other factors may also be to blame........ http://www.lung-cancer-blog.com/blogs/permalinks/1-2010/lung-cancer-mystery.html The volcanic eruptions thought responsible for Earth's largest mass extinction which killed more than 70 percent of plants and animals 250 million years ago is still taking lives today. That's the conclusion of a newly released study showing, for the first time, that the high silica content of coal in one region of China appears to be interacting with volatile substances in the coal to cause uncommonly high rates of lung cancer. The study, which helps solve this cancer mystery, appears in ACS' Environmental Science and Technology, a semi-monthly publication........ http://www.lung-cancer-blog.com/blogs/permalinks/12-2009/destruction-of-a-tumor-suppressor.html Scientists from the Indiana University School of Medicine and his colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage cancers, disables genes that suppress the growth of tumors. The finding may lead to the development of new drugs for late stage breast cancer and other difficult to treat malignancies........ http://www.lung-cancer-blog.com/blogs/permalinks/12-2009/lung-cancer-overall-survival-rates-improving.html Research released in the December 2009 issue of the Journal of Thoracic Oncology sought to determine whether the survival improvement among patients with metastatic lung cancer has improved over the last two decades as reported in controlled clinical trials. Scientists performed an analysis of over 100,000 patients with stage IV non-small cell lung cancer (NSCLC) identified through the SEER database to evaluate trends in survival between 1990 and 2005 to assess the true impact of recent medical advances on these patients. Daniel Morgensztern, MD of the Washington University School of Medicine and his team evaluated over 16 years of records from those in the unselected representative patient population and found a modest, but statistically significant, improvement in overall survival rates. Specifically, one-year overall survival increased from 13.2 percent to 19.4 percent. Additionally, two-year overall survival increased from 4.5 percent to 7.8 percent........ http://www.lung-cancer-blog.com/blogs/permalinks/11-2009/identifying-high-risk-people-for-lung-cancer.html A study featured in the recent issue of the Journal of Thoracic Oncology confirms the success of a simple questionnaire designed to identify patients at high risk of lung cancer. Initiated in 2001, the current study confirmed 18 cases of cancer of the original 430 patients who qualified as high risk after completing a five-minute questionnaire........ http://www.lung-cancer-blog.com/blogs/permalinks/10-2009/genes-that-increases-risk-of-lung-cancer.html A recent study reported in the October 2009 issue of the Journal of Thoracic Oncology determined that variations of specific genetic markers identified in prior research, or SNPs, may indicate a greater lung cancer risk in African Americans than in whites. The genes CHRNA3 and CHRNA5 may contribute to lung cancer risk due directly or through their association with nicotine dependence. Eventhough their presence is less frequent in African Americans, the risk for lung cancer appears to be greater when present........ http://www.lung-cancer-blog.com/blogs/permalinks/5-2009/women-more-vulnerable-to-tobacco-carcinogens.html Women appears to be more vulnerable than men to the cancer-causing effects of smoking tobacco, as per new results reported this week at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), Lugano, Switzerland. Swiss scientists studied 683 patients with lung cancer who were referred to a cancer centre in St Gallen between 2000 and 2005 and found women tended to be younger when they developed the cancer, despite having smoked on average significantly less than men........ http://www.lung-cancer-blog.com/blogs/permalinks/4-2009/racial-disparities-in-the-treatment-of-lung-cancer.html Black patients suffering from lung cancer are less likely to receive recommended chemotherapy and surgery than white patients with lung cancer, a disparity that shows no signs of lessening. That is the conclusion of a newly released study reported in the May 15, 2009 issue of CANCER, a peer-evaluated journal of the American Cancer Society. The study's findings indicate that efforts are needed to provide appropriate therapys for black patients and to educate them about the value of those therapys........ http://www.lung-cancer-blog.com/blogs/permalinks/1-2009/to-improve-lung-cancer-risk.html About 1100 people each year die in the UK from lung cancer correlation to indoor radon, but current government protection policies focus mainly on the small number of homes with high radon levels and neglect the 95% of radon related deaths caused by lower levels of radon, as per a research studypublished on bmj.com today........